Structural Elucidation of Phospholipids by Soft-ionization Mass Spectrometry
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- HAYASHI Akira
- Kansai Lipid Institute
Bibliographic Information
- Other Title
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- ソフトイオン化質量分析によるリン脂質の構造解析
- ソフト イオンカ シツリョウ ブンセキ ニ ヨル リン シシツ ノ コウゾウ
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Abstract
Advances in structure elucidation of glycero-and sphingo-phospholipids including phosphonolipids by soft ionization mass spectrometry for the past eight years are reviewed. This method enables identification of phospholipid class (polar head group), molecular weight, and molecular species of the hydrophobic moiety that includes total carbon number, number and position of double bond, and positional isomer (sn-1 or sn-2) of constituent fatty acids. As soft-ionization technique, ionization by fast atom bombardment (FAB), electrospray (ES) or matrix assisted laser desorption (MALD) are described on its principle, method and information obtained from its yielded molecular ions, fragment ions and product ions that are produced from MS/MS of precursor ion. The mass spectrometer referred are magnetic sector, quadrupole, time-of-flight and Fourier-transform ion cyclotron resonance types. Diacyl and ether-linked species were differentiated by the presence of only one carboxylate ion in the ether-linked species.
Journal
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- Journal of Japan Oil Chemists' Society
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Journal of Japan Oil Chemists' Society 47 (10), 983-996,1144, 1998
Japan Oil Chemists' Society
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Details 詳細情報について
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- CRID
- 1390282679068156928
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- NII Article ID
- 10002276871
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- NII Book ID
- AN10512582
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- ISSN
- 18841996
- 13418327
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- NDL BIB ID
- 4585431
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed