魚 (アユとマコガレイ) の脳・肝臓に分布するガングリオシドの比較

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  • Comparison of Gangliosides in Brain and Liver of Two Fish Species, <I>Plecoglossus altivelis</I> and <I>Limanda yokohamae</I>
  • サカナ アユ ト マコガレイ ノ ノウ カンゾウ ニ ブンプ スル ガングリオシド ノ ヒカク

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For Plecoglossus altivelis and Limanda yokohamae grown in different ecological environments, ganglioside characteristics in the brain and liver were examined and compared by TLC.<BR>As with sardine reported previously, polysialogangliosides having three or more sialic acid molecules bonded to each other were found present in the brain at high concentrations, while monosialoganglioside concentration in the liver was high.<BR>These findings confirm organ-specificity. In Limanda yokohamae liver, GM2 was the main component present at 79.5%, GM4 and GD1a were detected, respectively, at 24.4% and 22.3% in Plecoglossus altivelis liver. These data differ from those for sardine whose GM4 content was 47.4%, suggesting remarkable differences among fish species. GM3 is the major component in higher vertebrate livers, and thus species-specificity may be considered reflected by ganglioside distribution in the liver.

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  • 日本油化学会誌

    日本油化学会誌 48 (12), 1407-1410,1420, 1999

    公益社団法人 日本油化学会

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