Generation of Tetracosahexaenoic Acid in Benthic Marine Organisms
-
- Suo Rei
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
-
- Li Haoqi
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
-
- Yoshinaga Kazuaki
- Tsukishima Foods Industry Co. Ltd.
-
- Nagai Toshiharu
- Tsukishima Foods Industry Co. Ltd.
-
- Mizobe Hoyo
- Tsukishima Foods Industry Co. Ltd.
-
- Kojima Koichi
- Tsukishima Foods Industry Co. Ltd.
-
- Nagao Koji
- Department of Applied Biochemistry and Food Science, Saga University
-
- Beppu Fumiaki
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
-
- Gotoh Naohiro
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
この論文をさがす
抄録
Tetracosahexaenoic acid (THA, 24:6n-3) has been shown to have the strongest ability to suppress accumulation of lipids in HepG2 cells among well-known n-3 highly unsaturated fatty acids, such as EPA and DHA. In this study, a method for mass production of THA was investigated using distributions of THA and DHA in thirty-two marine organisms, such as starfishes, right-eyed flounders, shellfishes, and sharks. The fatty acid composition of the marine organisms was analyzed using GC-FID and THA was detected in starfish, right-eyed flounder, and shark. Furthermore, the ratio of DHA and THA (DHA/THA) in each sample was calculated using chromatogram peak area of GC-FID, and the value was found to be lower than 1 in some starfishes. As a result, THA was thought to be synthesized in the starfishes. In contrast, the value of DHA/THA for right-eyed flounder and sharks was greater than 1. The THA accumulation in right-eyed flounder was considered to be because of the starfishes that the flounder consumes as part of its diet. DHA is synthesized from THA by beta-oxidation in peroxisomes, in the Sprecher’s shunt. The high accumulation of THA observed in the flounder would be caused by the decreasing enzyme activation due to beta-oxidation in the peroxisomes of the starfishes. Understanding the differences in THA between aquatic species could also potentially allow us to understand why THA is generated in marine animals.
収録刊行物
-
- Journal of Oleo Science
-
Journal of Oleo Science 64 (7), 721-727, 2015
公益社団法人 日本油化学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282679069505280
-
- NII論文ID
- 130005085919
-
- NII書誌ID
- AA11503337
-
- ISSN
- 13473352
- 13458957
-
- NDL書誌ID
- 026523323
-
- PubMed
- 26136172
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可