Ligand-Exchange Kinetics of Fe(III)-Citrte Complex with Desferrioxamine B in the Presence of Divalent Metals

DOI
  • ITO Hiroaki
    Dept. of Civil and Environmental Engineering, Tohoku University
  • FUJII Manabu
    Dept. of Civil and Environmental Engineering, Tohoku University
  • SASAKI Shiori
    Dept. of Civil and Environmental Engineering, Tohoku University
  • WAITE T.David
    Dept. of Civil and Environmental Engineering, The University of New South Wales
  • OMURA Tatsuo
    Dept. of Civil and Environmental Engineering, Tohoku University

Bibliographic Information

Other Title
  • 二価金属存在下におけるクエン酸第二鉄錯体とDesferrioxamine Bのリガンド交換動力学

Abstract

We have developed a kinetic model for ligand-exchange reaction of ferric iron-citrate complex (FeCit) with desferrioxamine B (DFB) in the presence of divalent metals (Ca and Mg). The kinetic model considers (1) a disjunctive pathway where DFB binds to Fe following the dissociation of FeCit and (2) an adjunctive pathway where FeDFB is formed via the direct association of DFB to FeCit. The rate constants for the complex reaction in the disjunctive pathway estimated from the model well described the experimentally determined rate constants. In the adjunctive pathway, the reaction rate was found to be affected by the concentrations of divalent cations and citrate. The kinetic data in the adjunctive pathway was well explained by involving the effect of direct association of divalent cation to the precursor complex. The results indicated the significant effect of divalent cations on the kinetics for the ligandexchange of iron-citrate complex with DFB.

Journal

Details 詳細情報について

  • CRID
    1390282679088056704
  • NII Article ID
    130003775876
  • DOI
    10.11532/proes1992.44.115
  • ISSN
    1884829X
    13415115
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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