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26Al tracer experiment by accelerator mass spectrometry and its application to the studies for amyotrophic lateral sclerosis and Alzheimer's disease. I.
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- KOBAYASHI Koichi
- Research Center for Nuclear Science and Technology, University of Tokyo
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- YUMOTO Sakae
- Department of Anatomy, Faculty of Medicine, University of Tokyo
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- NAGAI Hisao
- College of Humanities and Sciences, Nihon University
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- HOSOYAMA Yoshiyuki
- College of Humanities and Sciences, Nihon University
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- IMAMURA Mineo
- Institute for Nuclear Study, University of Tokyo
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- MASUZAWA Shin-ichirou
- College of Humanities and Sciences, Nihon University
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- KOIZUMI Yoshinobu
- Radioisotope Center, University of Tokyo
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- YAMASHITA Hiroshi
- Department of Physics, Faculty of Science, University of Tokyo
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Description
Accelerator mass spectrometry (AMS) was applied for 26Al tracer experiment to study the aluminum toxicity and metabolism in rats. To investigate the cause of amyotrophic lateral sclerosis (ALS) and Alzheimer's disease, the aluminum incorporation into the brain (cerebrum) was studied by AMS using 26Al as a tracer. When 26Al was intraperitoneally injected into rats, a considerable amount of 26Al was incorporated into the cerebrum after 5-35 days of the injection.
Journal
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- Proceedings of the Japan Academy, Series B
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Proceedings of the Japan Academy, Series B 66 (10), 189-192, 1990
The Japan Academy
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Keywords
Details 詳細情報について
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- CRID
- 1390282679121888256
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- NII Article ID
- 130000906863
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- COI
- 1:CAS:528:DyaK3MXitVWht7o%3D
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- ISSN
- 13492896
- 03862208
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed