Phosphoinositede-binding interface proteins involved in the shaping cell membrane

  • TAKENAWA Tadaomi
    Laboratory of Lipid Biochemistry, Graduate School of Medicine, Kobe University

書誌事項

タイトル別名
  • Phosphoinositide-binding interface proteins involved in shaping cell membranes

この論文をさがす

抄録

The mechanism by which cell and cell membrane shapes are created has long been a subject of great interest. Among the phosphoinositide-binding proteins, a group of proteins that can change the shape of membranes, in addition to the phosphoinositide-binding ability, has been found. These proteins, which contain membrane-deforming domains such as the BAR, EFC/F-BAR, and the IMD/I-BAR domains, led to inward-invaginated tubes or outward protrusions of the membrane, resulting in a variety of membrane shapes. Furthermore, these proteins not only bind to phosphoinositide, but also to the N-WASP/WAVE complex and the actin polymerization machinery, which generates a driving force to shape the membranes.<BR><BR>(Communicated by Takao SEKIYA, M.J.A.)

収録刊行物

被引用文献 (3)*注記

もっと見る

参考文献 (106)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ