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Mumiamicin: Structure and bioactivity of a new furan fatty acid from <i>Mumia</i> sp. YSP-2-79
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- Kimura Tōru
- Graduate School of Infection Control Sciences, Kitasato University
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- Tajima Ayano
- School of Marine Biosciences, Kitasato University
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- Inahashi Yuki
- Kitasato Institute for Life Sciences, Kitasato University
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- Iwatsuki Masato
- Graduate School of Infection Control Sciences, Kitasato University Kitasato Institute for Life Sciences, Kitasato University
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- Kasai Hiroaki
- School of Marine Biosciences, Kitasato University
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- Mokudai Takayuki
- Tohoku University Graduate School of Dentistry
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- Niwano Yoshimi
- Tohoku University Graduate School of Dentistry
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- Shiomi Kazuro
- Graduate School of Infection Control Sciences, Kitasato University Kitasato Institute for Life Sciences, Kitasato University
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- Takahashi Yōko
- Kitasato Institute for Life Sciences, Kitasato University
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- Ōmura Satoshi
- Kitasato Institute for Life Sciences, Kitasato University
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- Nakashima Takuji
- Kitasato Institute for Life Sciences, Kitasato University
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Description
<p>A new antibiotic, designated mumiamicin, was isolated from the cultured broth of the rare actinomycete strain, Mumia sp. YSP-2-79, by Diaion HP-20, silica gel and ODS column chromatography, followed by HPLC purification. The chemical structure of mumiamicin was elucidated as a new furan fatty acid by nuclear magnetic resonance and mass spectrometry. Mumiamicin showed antimicrobial activity and antioxidative activity.</p>
Journal
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- The Journal of General and Applied Microbiology
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The Journal of General and Applied Microbiology 64 (2), 62-67, 2018
Applied Microbiology, Molecular and Cellular Biosciences Research Foundation
