Microbial metabolites with inhibitory activity against lipid metabolism
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- TOMODA Hiroshi
- Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University
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- NAMATAME Ichiji
- Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University Japan Society for the Promotion of Science
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- OMURA Satoshi
- Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University
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Abstract
Microbial products inhibiting lipid metabolism, particularly involved in the fatty acid and cholesterol metabolic pathways were screened with various assay systems. Inhibitors were discovered for fatty acid synthase, acyl-coenzyme A (CoA) synthetase and diacylglycerol acyltransferase in fatty acid metabolism and 3-hydroxy-3-methylglutaryl-CoA synthase, acyl-CoA:cholesterol acyltransferase and cholesteryl ester transfer protein in cholesterol metabolism.
Journal
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- Proceedings of the Japan Academy, Series B
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Proceedings of the Japan Academy, Series B 78 (8), 217-240, 2002
The Japan Academy
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Keywords
Details 詳細情報について
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- CRID
- 1390282679124003968
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- NII Article ID
- 130000907744
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- NII Book ID
- AA00785485
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- ISSN
- 13492896
- 03862208
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- NDL BIB ID
- 6366993
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed