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- SHIMOJO Emi
- Section of Internal Medicine and Gastroenterology, International Medical Center of Japan
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- YAMAGUCHI Isomaro
- Department of Applied Biological Chemistry, The University of Tokyo
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- MUROFUSHI Noboru
- Department of Applied Biological Chemistry, The University of Tokyo
Bibliographic Information
- Other Title
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- Increase of Indole-3-acetic Acid in Hum
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Abstract
The contents of indole-3-acetic acid in the normal tissues and squamous cell carcinoma obtained from patients with esophageal cancer were determined by gas chromatography/high resolution-selected ion monitoring mass spectrometry. The contents of indole-3-acetic acid in cancer tissues were higher than those in neighboring normal tissues. The contents in normal tissues and squamous cell carcinoma are in the range of 90-390ng/g fw and in the range of 1400-4700ng/g fw, respectively. These data show that the production of indole-3-acetic acid was activated in the squamous cell carcinoma at the early differentiating stage. The increase of indole-3-acetic acid may concern the stimulation of the multiplication of esophageal cancer cells or the formation of such an inhibitor as indole-3-carbinol.
Journal
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- Proceedings of the Japan Academy, Series B
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Proceedings of the Japan Academy, Series B 73 (8), 182-185, 1997
The Japan Academy
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Details 詳細情報について
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- CRID
- 1390282679124290176
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- NII Article ID
- 130000903010
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- NII Book ID
- AA00785485
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- ISSN
- 13492896
- 03862208
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- NDL BIB ID
- 4371343
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed