Treatment of rheumatoid arthritis with biological agents — as a typical and common immune-mediated inflammatory disease

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  • TAKEUCHI Tsutomu
    Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine

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  • Treatment of rheumatoid arthritis with biological agents : as a typical and common immune-mediated inflammatory disease

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Abstract

<p>Molecules involved in the disease process facilitated our understanding of pathogenesis of the disease with unknown etiology such as immune-mediated and inflammatory diseases. Moreover, the targeted therapies against the proposed molecular targets by biological agents provide enormous benefits to the patients and societies. Here, I will review recent progress of the biological treatment in the immune-inflammatory diseases by focusing on the rheumatoid arthritis, the disease characterized by persistent polyarthritis leading to joint destruction and disability with autoimmune features, as a role model.</p>

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