Bhimamycin A-E and Bhimanone: Isolation, Structure Elucidation and Biological Activity of Novel Quinone Antibiotics from a Terrestrial Streptomycete
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- FOTSO SERGE
- Department of Organic Chemistry, University of Göttingen
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- MASKEY RAJENDRA P.
- Department of Organic Chemistry, University of Göttingen
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- GRÜN-WOLLNY IRIS
- bioLeads GmbH
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- SCHULZ KLAUS-PETER
- Department of Chemistry and Biochemistry, Arizona State University
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- MUNK MORTON
- Department of Chemistry and Biochemistry, Arizona State University
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- LAATSCH HARTMUT
- Department of Organic Chemistry, University of Göttingen
抄録
From the ethyl acetate extract of a terrestrial Streptomycete isolate, five new quinone antibiotics, bhimamycin A (2a), B (2b), C (3c), D (5a), E (7) and the new tetralone bhimanone (8) were isolated together with the known microbial products chrysophanol (1a), aloesaponarin II (1b), 3, 8-dihydroxy-1-methylanthraquinone-2-carboxylic acid (1c), adenosine, 2'-deoxyadenosine, phenylacetamide, and 2-(p-hydroxyphenyl)ethanol. The structures of these natural products were deduced from the spectral data and confirmed by comparison with related compounds from the literature and by synthesis.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 56 (11), 931-941, 2003
公益財団法人 日本感染症医薬品協会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282679125149824
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- NII論文ID
- 130003410479
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- COI
- 1:CAS:528:DC%2BD3sXpsV2htrY%3D
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- ISSN
- 18811469
- 00218820
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可