Reveromycins, new inhibitors of eukaryotic cell growth. I. Producing organism, fermentation, isolation and physico-chemical properties.
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- TAKAHASHI HIDETOSHI
- Research Institute of Life Science, Snow Brand Milk Products Co., Ltd.
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- OSADA HIROYUKI
- RIKEN, The Institute of Physical and Chemical Research
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- KOSHINO HIROYUKI
- RIKEN, The Institute of Physical and Chemical Research
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- KUDO TAKUJI
- RIKEN, The Institute of Physical and Chemical Research
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- AMANO SHUICHI
- RIKEN, The Institute of Physical and Chemical Research
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- SHIMIZU SHINJI
- Research Institute of Life Science, Snow Brand Milk Products Co., Ltd.
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- YOSHIHAMA MAKOTO
- Research Institute of Life Science, Snow Brand Milk Products Co., Ltd.
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- ISONO KIYOSHI
- RIKEN, The Institute of Physical and Chemical Research Present address: Department of Marine Science, School of Marine Science and Technology, Tokai University
書誌事項
- タイトル別名
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- I. PRODUCING ORGANISM, FERMENTATION, ISOLATION AND PHYSICO-CHEMICAL PROPERTIES
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説明
New antibiotics named reveromycins A, B, C and D were isolated as inhibitors of mitogenic activity induced by epidermal growth factor (EGF) in a mouse epidermal keratinocyte. Reveromycins were produced by a soil actinomycete (strain SN-593) which belongs to the genus Streptomyces.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 45 (9), 1409-1413, 1992
公益財団法人 日本感染症医薬品協会
