Reveromycins, new inhibitors of eukaryotic cell growth. I. Producing organism, fermentation, isolation and physico-chemical properties.

DOI PubMed 6 Citations Open Access
  • TAKAHASHI HIDETOSHI
    Research Institute of Life Science, Snow Brand Milk Products Co., Ltd.
  • OSADA HIROYUKI
    RIKEN, The Institute of Physical and Chemical Research
  • KOSHINO HIROYUKI
    RIKEN, The Institute of Physical and Chemical Research
  • KUDO TAKUJI
    RIKEN, The Institute of Physical and Chemical Research
  • AMANO SHUICHI
    RIKEN, The Institute of Physical and Chemical Research
  • SHIMIZU SHINJI
    Research Institute of Life Science, Snow Brand Milk Products Co., Ltd.
  • YOSHIHAMA MAKOTO
    Research Institute of Life Science, Snow Brand Milk Products Co., Ltd.
  • ISONO KIYOSHI
    RIKEN, The Institute of Physical and Chemical Research Present address: Department of Marine Science, School of Marine Science and Technology, Tokai University

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Other Title
  • I. PRODUCING ORGANISM, FERMENTATION, ISOLATION AND PHYSICO-CHEMICAL PROPERTIES

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Description

New antibiotics named reveromycins A, B, C and D were isolated as inhibitors of mitogenic activity induced by epidermal growth factor (EGF) in a mouse epidermal keratinocyte. Reveromycins were produced by a soil actinomycete (strain SN-593) which belongs to the genus Streptomyces.

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Details 詳細情報について

  • CRID
    1390282679125256448
  • NII Article ID
    130003502366
  • DOI
    10.7164/antibiotics.45.1409
  • COI
    1:CAS:528:DyaK3sXhvV2gsA%3D%3D
  • ISSN
    18811469
    00218820
    http://id.crossref.org/issn/00218820
  • PubMed
    1429225
  • Text Lang
    en
  • Article Type
    journal article
  • Data Source
    • JaLC
    • Crossref
    • PubMed
    • CiNii Articles
    • OpenAIRE
  • Abstract License Flag
    Disallowed

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