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- TANAKA HARUO
- The Kitasato Institute and Kitasato University
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- KOYAMA YASUAKI
- The Kitasato Institute and Kitasato University
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- AWAYA JUICHI
- The Kitasato Institute and Kitasato University
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- MARUMO HIROFUTO
- Pharmaceutical Res. Labs., Kyowa Hakko Kogyo Co. Ltd.
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- OIWA RUIKO
- The Kitasato Institute and Kitasato University
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- KATAGIRI MICHIKO
- The Kitasato Institute and Kitasato University
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- NAGAI TOSHIAKI
- The Kitasato Institute and Kitasato University
書誌事項
- タイトル別名
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- Nanaomycins, new antibiotics produced by a strain of Streptomyces. I. Taxonomy, isolation, characterization and biological properties.
- Nanaomycins, new antibiotics produced by a strain of Streptomyces. I. Taxonomy, isolation, characterization and biological prooerties
- Nanaomycins, new antibiotics produced by a strain of Streptomyces
- I. TAXONOMY, ISOLATION, CHARACTERIZATION AND BIOLOGICAL PROPERTIES
- 公開日
- 1975
- 資源種別
- journal article
- DOI
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- 10.7164/antibiotics.28.860
- 公開者
- 公益財団法人 日本感染症医薬品協会
この論文をさがす
説明
Nanaomycins are new antibiotics produced by the strain OS-3966 which was designated Streptomyces rosa var. notoensis. Nanaomycins A and B were isolated from the culture filtrate by extraction with organic solvent and silica gel chromatography. The physical and chemical properties suggest that nanaomycins A and B are quinone-related compounds having the molecular formulae, C16H14O6 and C16H16O7, respectively. Nanaomycins A and B inhibit mainly mycoplasmas, fungi and Gram-positive bacteria. The acute toxicities (LD50. ip) of nanaomycins A and B in mice are 28.2 and 169 mg/kg, respectively.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 28 (11), 860-867, 1975
公益財団法人 日本感染症医薬品協会