Antibacterial effects of Cefroxadine, Cephalexin and Cephradine in a new in vitro pharmacokinetic model.
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- SCHNEIDER P.
- Research Department, Pharmaceuticals Division, Ciba-Geigy Limited
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- TOSCH W.
- Research Department, Pharmaceuticals Division, Ciba-Geigy Limited
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- MAURER M.
- Research Department, Pharmaceuticals Division, Ciba-Geigy Limited
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- ZAK O.
- Research Department, Pharmaceuticals Division, Ciba-Geigy Limited
Bibliographic Information
- Other Title
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- Antibacterial Effects of Cefroxadine Ce
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Abstract
A pharmacokinetic model has been developed, by means of which all possible time courses of the concentrations of antibiotics in the plasma of treated individuals can be exactly simulated in vitro without diluting the test organism and affecting the growth curves. Equieffective concentrations in the system corresponded to the plasma concentrations in man produced by cefroxadine in a single oral dose of 250 mg and cephalexin and cephradine in a single oral dose of 500 mg.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 35 (7), 843-849, 1982
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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Keywords
Details 詳細情報について
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- CRID
- 1390282679126614016
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- NII Article ID
- 130003500273
- 40005315153
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- NII Book ID
- AA0069330X
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- ISSN
- 18811469
- 00218820
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- NDL BIB ID
- 2494291
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- PubMed
- 7174537
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed