Adenophostins A and B: Potent agonists of inositol-1,4,5-trisphosphate receptor produced by Penicillium brevicompactum. Taxonomy, fermentation, isolation, physico-chemical and biological properties.

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  • TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

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New inositol-1, 4, 5-trisphosphate (InsP3) agonists, adenophostins A(1) and B(2), were isolated from the culture broth of Penicillium brevicompactum SANK 11991 and SANK 12177. Its structures were related to adenine nucleotides. The agonistic activity of adenophostins A or B for binding to the InsP3 receptor was higher than InsP3 itself.

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Details 詳細情報について

  • CRID
    1390282679127281280
  • NII Article ID
    130003502415
  • DOI
    10.7164/antibiotics.46.1643
  • COI
    1:CAS:528:DyaK2cXht12isbw%3D
  • ISSN
    18811469
    00218820
  • PubMed
    8270485
  • Text Lang
    en
  • Article Type
    journal article
  • Data Source
    • JaLC
    • Crossref
    • PubMed
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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