Enhancement of cerulenin production by a natural zeolite, an ammonium ion-trapping agent.
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- MASUMA ROKUROU
- School of Pharmaceutical Sciences, Kitasato University
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- TANAKA YOSHITAKE
- School of Pharmaceutical Sciences, Kitasato University
Bibliographic Information
- Other Title
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- Enhancement of Cerulenin Production by
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Description
Addition of a natural zeolite, a known ammonium ion-trapping agent, to a complex medium resulted in a several fold increase in cerulenin production by Cephalosporium caerulens. In the presence of zeolite, ammonium ion in the medium decreased, while mycelial growth increased to a small extent, and pH values remained constant. Small amounts of ammonium bicarbonate inhibited cerulenin production without affecting mycelial growth and pH values. It is thus assumed that zeolite stimulated cerulenin production by releasing the biosynthesis from the suppression by ammonium ions in C. caerulens.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 35 (9), 1184-1193, 1982
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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Details 詳細情報について
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- CRID
- 1390282679128115200
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- NII Article ID
- 130003409316
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- NII Book ID
- AA0069330X
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- COI
- 1:CAS:528:DyaL38XmtFCitLY%3D
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- ISSN
- 18811469
- 00218820
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- NDL BIB ID
- 2498661
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- PubMed
- 6292149
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed