Pyralomicins, Novel Antibiotics from Microtetraspora spiralis. III. Biosynthesis of Pyralomicin 1a.

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  • III. Biosynthesis of Pyralomicin 1a

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The biosynthesis of pyralomicin la (1) was studied by feeding of 13C and 15N labeled compounds to the culture of Microtetraspora spiralis MI178-34F18. The result indicated that the benzopyranopyrrole unit of 1 was derived from two units of acetate, one unit of propionate and one unit of proline, and that the cyclitol unit of 1 was derived from glucose metabolites. And 4'-O-CH3 was derived from the S-CH3 group of methionine.

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Details 詳細情報について

  • CRID
    1390282679128323712
  • NII Article ID
    130003503139
  • DOI
    10.7164/antibiotics.49.657
  • COI
    1:CAS:528:DyaK28Xks1eqsLs%3D
  • ISSN
    18811469
    00218820
  • PubMed
    8784425
  • Text Lang
    en
  • Article Type
    journal article
  • Data Source
    • JaLC
    • Crossref
    • PubMed
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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