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Pyralomicins, Novel Antibiotics from Microtetraspora spiralis. III. Biosynthesis of Pyralomicin 1a.
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- KAWAMURA NAOTO
- Institute of Microbial Chemistry
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- SAWA RYUICHI
- Institute of Microbial Chemistry
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- TAKAHASHI YOSHIKAZU
- Institute of Microbial Chemistry
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- SAWA TSUTOMU
- Institute of Microbial Chemistry
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- NAGANAWA HIROSHI
- Institute of Microbial Chemistry
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- TAKEUCHI TOMIO
- Institute of Microbial Chemistry
Bibliographic Information
- Other Title
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- III. Biosynthesis of Pyralomicin 1a
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Description
The biosynthesis of pyralomicin la (1) was studied by feeding of 13C and 15N labeled compounds to the culture of Microtetraspora spiralis MI178-34F18. The result indicated that the benzopyranopyrrole unit of 1 was derived from two units of acetate, one unit of propionate and one unit of proline, and that the cyclitol unit of 1 was derived from glucose metabolites. And 4'-O-CH3 was derived from the S-CH3 group of methionine.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 49 (7), 657-660, 1996
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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Keywords
Details 詳細情報について
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- CRID
- 1390282679128323712
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- NII Article ID
- 130003503139
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- COI
- 1:CAS:528:DyaK28Xks1eqsLs%3D
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- ISSN
- 18811469
- 00218820
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- PubMed
- 8784425
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed