Spirofungin, a new antifungal antibiotic from Streptomyces violaceusniger Tu 4113

HÖLTZEL ALEXANDRA, KEMPTER CHRISTOPH, METZGER JÖRG W., JUNG GÜNTHER, GROTH INGRID, FRITZ THOMAS, FIEDLER HANS-PETER

doi:10.7164/antibiotics.51.699

Spirofungin, a new antifungal antibiotic from Streptomyces violaceusniger Tu 4113

DOI PubMed 被引用文献9件

HÖLTZEL ALEXANDRA

Institut für Organische Chemie, Universität Tübingen
KEMPTER CHRISTOPH

Institut für Organische Chemie, Universität Tübingen
METZGER JÖRG W.

Institut für Organische Chemie, Universität Tübingen
JUNG GÜNTHER

Institut für Organische Chemie, Universität Tübingen
GROTH INGRID

Hans-Knöll-Institut für Naturstoff-Forschung e.V.
FRITZ THOMAS

Biologisches Institut, Universität Tübingen
FIEDLER HANS-PETER

Biologisches Institut, Universität Tübingen

書誌事項

タイトル別名

Spirofungin, a New Antifungal Antibiotic from Streptomyces violaceusniger Tue 4113.
Spirofungin, a new antifungal antibiotic from Streptomyces violaceusniger Tü 4113

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説明

A new secondary metabolite was detected in the culture filtrate and extracts of Streptomyces violaceusniger Tü 4113 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. The compound named spirofungin has a polyketide-spiroketal structure and shows various antifungal activities, particularly against yeasts.