KALAFUNGIN, A NEW BROAD SPECTRUM ANTIBIOTIC
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- BERGY M. E.
- Research Laboratories, The Upjohn Company
Bibliographic Information
- Other Title
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- Kalafungin,a new broad spectrum antibiotic isolation and characterization
- ISOLATION AND CHARACTERIZATION
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Abstract
Kalafungin is a new antibiotic extracted from the fermentation broth of Streptomyces tanashiensis strain Kala, and purified by chromatography on silica gel followed by crystallization. It is a weakly acidic, orange colored compound, pKa=10.0, with a molecular formula C16H12O6 and a molecular weight of 300. It is dextrorotatory in chloroform, [α]25D+159, and exhibits ultraviolet and visible absorption maxima at 212, 256, and 425 mμ in methanol.<br> Kalafungin melts at 163-166°C and is readily soluble in ethyl acetate, chloroform, and acetone but only slightly soluble in water.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 21 (7), 454-457, 1968
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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Keywords
Details 詳細情報について
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- CRID
- 1390282679128910592
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- NII Article ID
- 130003498109
- 10008469835
- 40018688278
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- NII Book ID
- AA0069330X
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- COI
- 1:CAS:528:DyaF1MXit1yltA%3D%3D
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- ISSN
- 18811469
- 00218820
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- NDL BIB ID
- 8509934
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- PubMed
- 4303501
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed