The structure of permetin A, a new polypeptin type antibiotic produced by Bacillus circulans.
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- TAKEUCHI YOKO
- Central Research Laboratories, Ajinomoto Co., Inc.
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- MURAI ASAO
- Central Research Laboratories, Ajinomoto Co., Inc.
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- TAKAHARA YOSHIYUKI
- Central Research Laboratories, Ajinomoto Co., Inc.
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- KAINOSHO MASATSUNE
- Central Research Laboratories, Ajinomoto Co., Inc.
書誌事項
- タイトル別名
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- structure of permetin A a new polypepti
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抄録
The structure of permetin A(I), an antibiotic substance produced by Bacillus circalans AJ 3902, has been elucidated as a cyclic acyl peptide by means of the mass and nuclear magnetic resonance spectroscopic techniques. C2H5CH-CH-CH2-CO-L-DCb-L-Ile→L-Dob→D-Phe CH3O L-Ser←L-Leu←D-Val←L-Dab←L-Leu The structure was found to be the same as polypeptin A(II) except that L-Thr in II is replaced by L-Ser in I. Details of the structural determination are given for the permetin A itself as well as for the hydrolyzed permetin A. C2H5CH-CH-CH2-CO→L-Dab→L-Ile→L-Dab→D-Phe CH3 O L-Thr←L-Leu←D-VoI←L-Dob-L-Leu II
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 32 (2), 121-129, 1979
公益財団法人 日本感染症医薬品協会
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詳細情報 詳細情報について
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- CRID
- 1390282679130113792
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- NII論文ID
- 130003499616
- 40005314337
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- NII書誌ID
- AA0069330X
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- COI
- 1:CAS:528:DyaL3cXmvFWr
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- ISSN
- 18811469
- 00218820
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- NDL書誌ID
- 2079826
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- PubMed
- 438100
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可