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STUDIES ON A SESQUITERPENE ANTIBIOTIC, COMPOUND A-2, MINOR COMPONENT FROM <i>MYROTHECIUM.</i> I
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- OKUCHI MASAO
- Laboratory of Fermentation Chemistry, Department of Agricultural Chemistry, College of Agriculture, Nagoya University Present address: Tokyo Research Institute, Kowa Co., Ltd.
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- ITOH MASAO
- Laboratory of Fermentation Chemistry, Department of Agricultural Chemistry, College of Agriculture, Nagoya University
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- KANEKO YASUYUKI
- Laboratory of Fermentation Chemistry, Department of Agricultural Chemistry, College of Agriculture, Nagoya University
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- Doi SHINJI
- Laboratory of Fermentation Chemistry, Department of Agricultural Chemistry, College of Agriculture, Nagoya University Present address: Laboratory of Applied Microbiology, College of Agriculture, Meijo University
Bibliographic Information
- Other Title
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- STUDIES ON A SESQUITERPENE ANTIBIOTIC, COMPOUND A-2, MINOR COMPONENT FROM MYROTHECIUM. I
- FERMENTATION, ISOLATION, PURIFICATION, PHYSICOCHEMICAL PROPERTIES AND THE STRUCTURE
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Description
A new antifungal substance, compound A-2 was isolated from fermentation broth of a fungus which was identified as a new variety of Myrothecium verrucaria by the authors. It was obtained as colorless prisms melting at 147-148°C having the molecular formula C19H26O6. From the physicochemical properties and the structure, compound A-2 was concluded to be a new antifungal substance of sesquiterpene, 4, 15-diacetylverrucarol. This substance was active against fungi, especially Trychophyton rubrum.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 26 (10), 562-568, 1973
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION