Sorbistin, a new aminoglycoside antibiotic complex of bacterial origin. III. Structure determination.

KONISHI MASATAKA, KAMATA SACHIKO, TSUNO TAKASHI, NUMATA KEI-ICHI, TSUKIURA HIROSHI, NAITO TAKAYUKI, KAWAGUCHI HIROSHI

doi:10.7164/antibiotics.29.1152

Sorbistin, a new aminoglycoside antibiotic complex of bacterial origin. III. Structure determination.

DOI PubMed

KONISHI MASATAKA

Bristol-Banyu Research Institute, Ltd.
KAMATA SACHIKO

Bristol-Banyu Research Institute, Ltd.
TSUNO TAKASHI

Bristol-Banyu Research Institute, Ltd.
NUMATA KEI-ICHI

Bristol-Banyu Research Institute, Ltd.
TSUKIURA HIROSHI

Bristol-Banyu Research Institute, Ltd.
NAITO TAKAYUKI

Bristol-Banyu Research Institute, Ltd.
KAWAGUCHI HIROSHI

Bristol-Banyu Research Institute, Ltd.

書誌事項

タイトル別名

III. STRUCTURE DETERMINATION

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説明

The structures of sorbistins A₁, A₂, B, C and D have been determined including stereochemistry. Sorbistins A₁, A₂ and B are composed of a 4-acyl-amino-4-deoxy-D-glucose and 1, 4-diamino-1, 4-dideoxy-D-sorbitol, the latter compound being hitherto undescribed in literature. Sorbistins C and D have the same aglycone of 1, 4-diamino-1, 4-dideoxy-D-sorbitol, which is linked with D-glucose and 4-amino-4-deoxy-D-glucose, respectively, through a glycosidic bond.