Studies on Actinomycetales producing antibiotics only on agar culture. I. Screening, taxonomy and morphology-productivity relationship of Streptomyces halstedii, strain SF-1993.
-
- SHOMURA TAKASHI
- Central Research Laboratories, Meiji Seika Kaisha, Ltd.
-
- YOSHIDA JUNKO
- Central Research Laboratories, Meiji Seika Kaisha, Ltd.
-
- AMANO SHOICHI
- Central Research Laboratories, Meiji Seika Kaisha, Ltd.
-
- KOJIMA MICHIO
- Central Research Laboratories, Meiji Seika Kaisha, Ltd.
-
- INOUYE SHIGEHARU
- Central Research Laboratories, Meiji Seika Kaisha, Ltd.
-
- NIIDA TARO
- Central Research Laboratories, Meiji Seika Kaisha, Ltd.
書誌事項
- タイトル別名
-
- I. SCREENING, TAXONOMY AND MORPHOLOGY-PRODUCTIVITY RELATIONSHIP OF <i>STREPTOMYCES HALSTEDII</i>, STRAIN SF-1993
この論文をさがす
説明
Soil Actinomycetales that produce antibiotics during growth on agar but not in submerged culture were searched for and about 25 strains were obtained. One of these, Streptomyces halstedii, strain SF-1993, which produces an antibiotic designated SF-1993 was studied taxonomically and morphologically. The antibiotic-productivity of strain SF-1993 was correlated with mycelial morphology. The vegetative mycelium was filamentous in antibiotic-producing agar cultures, but fragmented in non-producing submerged cultures. By maintaining submerged cells filamentous, production of antibiotic in the submerged fermentations was accomplished. Filamentation was maintained by the use of diluted media or non-fragmented mutant substrains.
収録刊行物
-
- The Journal of Antibiotics
-
The Journal of Antibiotics 32 (5), 427-435, 1979
公益財団法人 日本感染症医薬品協会
