Ribostamycin, as an intermediate in the biosynthesis of neomycin.

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  • Ribostamycin as an intermediate in the

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A mutant of a neomycin-producing Streptomyces fradiae was found which synthesizes ribostamycin instead of neomycin. After a reverse mutation new colonies were obtained producing neomycin again. Ribostamycin might thus be considered as an intermediate in the biosynthesis of neomycin.

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