Rancinamycins, metabolites produced by Streptomyces lincolnensis in sulfur-depleted media.
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- ARGOUDELIS A. D.
- The Upjohn Company
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- PYKE T. R.
- The Upjohn Company
Bibliographic Information
- Other Title
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- Rancinamycins metabolites produced by S
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Abstract
Rancinamycins I, II, III and IV are secondary metabolites produced by Streptomyces lincolnensis in a sulfur-depleted culture medium. Rancinamycins I and II, the main components of the mixture, show broad spectrum antibiotic activity in vitro. Subcutaneously injected or<br>orally administered antibiotic afforded no protection for experimentally infected mice against lethal challenges of Staphylococcus aureus. Radioactive tracer studies failed to demonstrate that the rancinamycins were precursors in the biosynthesis of lincomycin.
Journal
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- The Journal of Antibiotics
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The Journal of Antibiotics 29 (8), 777-786, 1976
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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Details 詳細情報について
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- CRID
- 1390282679131688960
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- NII Article ID
- 130003408860
- 40005313959
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- NII Book ID
- AA0069330X
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- COI
- 1:CAS:528:DyaE28XlvFSlsrk%3D
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- ISSN
- 18811469
- 00218820
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- NDL BIB ID
- 1722503
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- PubMed
- 993114
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed