Studies on the ionophorous antibiotics-11-The artifacts and the degradation products of lysocellin
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- KOENUMA MITSUO
- Shionogi Research Laboratory, Shionogi & Co., Ltd.
書誌事項
- タイトル別名
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- Studies on the ionophorous antibiotics. XI. The artifacts and the degradation products of lysocellin.
- Studies on the ionophorous antibiotics
- THE ARTIFACTS AND THE DEGRADATION PRODUCTS OF LYSOCELLIN
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抄録
Lysocellin is a new polyether antibiotic produced by Streptomyces cacaoi var. asoensis and is characterized as a broad spectrum ionophore having a higher complexation affinity for divalent cations than for monovalents and also having an ability to transport biological amines.<br>The structures of two artifacts designated L1 and M1 have been elucidated based on spectral evidence, and the formation mechanism of these compounds was discussed with respect to the reactivity of the antibiotic. In addition, a number of degradation and modified products were prepared in order to examine their biological activity and to utilize as the model compounds for 13C-NMR assignment.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 30 (10), 819-828, 1977
公益財団法人 日本感染症医薬品協会
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詳細情報 詳細情報について
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- CRID
- 1390282679131728896
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- NII論文ID
- 130003499274
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- NII書誌ID
- AA0069330X
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- COI
- 1:CAS:528:DyaE1cXitVCruw%3D%3D
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- ISSN
- 18811469
- 00218820
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- NDL書誌ID
- 1913653
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- PubMed
- 412819
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可