書誌事項
- タイトル別名
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- Affinity for a Malignant Tumor and Organs of the Elements in Group V of the Periodic Table
- シュウキ リツ ダイVゾク ゲンソ ノ ガン オヨビ ゾウキ シンワセイ
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In order to investigate the tumor affinity radioisotopes, vanadium (V-48), niobium (Nb-95), tantalum (Ta-182), arsenic (As-74) and antimony (Sb-124) —the elements of group V in the periodic table—were examined, using the rats which were subcutaneously transplanted with Yoshida sarcoma. Six preparations, 48VO2Cl, 95Nb-oxalate, 182Ta-oxalate, Na2H74AsO4 (Na2HAsO40.008μg), Na2HAsO4 (Na2HAsO41 mg) and124Sb-chloride were injected intravenously to each group of tumor bearing rats. These rats were sacrificed at various periods after injection of each preparation: 3 hours, 24 hours and 48 hours in all preparations. The radioactivities of the tumor, blood, muscle, liver, kidney and spleen were measured by a well-type scintillation counter, and retention values in every tissue including the tumor were calculated (in percent of administered dose per g-tissue weight) .<BR>95Nb-oxalate had considerably strong affinity for the malignant tumor.48VO2Cl, 182Ta-oxalate, Na2H74AsO4and124Sb-chloride did not have any affinity for the malignant tumor. But48VO2Cl had fairly strong affinity for the kidney, Na2H74AsO4had very strong affinity for blood-corpuscles and strong affinity for the spleen.182Ta-oxalate and124Sb-chloride did not have any affinity for the organs and182Ta-oxalate was slowly excreted and124Sb-chloride was rapidly excreted in urine.
収録刊行物
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- RADIOISOTOPES
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RADIOISOTOPES 22 (6), 286-290, 1973
公益社団法人 日本アイソトープ協会
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詳細情報 詳細情報について
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- CRID
- 1390282679132776832
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- NII論文ID
- 130004380439
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- NII書誌ID
- AN00351589
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- ISSN
- 18844111
- 00338303
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- NDL書誌ID
- 7496018
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- データソース種別
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- JaLC
- NDL
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