Diagnostic Value of Female Genital Malignant Tumors by Using <SUP>111</SUP>In-Bleomycin Scintigraphy

DOI Web Site Web Site PubMed

Bibliographic Information

Other Title
  • <SUP>111</SUP>In-Bleomycin scintigraphyによる女性性器悪性腫瘍の診断的価値
  • 111In Bleomycin scintigraphy ニヨル ジョセイ セ

Search this article

Abstract

In order to know if it is possible to objectively decide the extent of infiltration of female genital malignant tumors into parametrium by using 111In-bleomycin scintigraphy, a fundamental and clinical investigation was made.<BR>The result was as follows; <BR>1) The radiochemical purity and stability of 111In-BLM were comparatively unchangeable. When this complex was kept at room temperature for a week, there was not more than 2% of the free 111In.<BR>2) As to blood clearance, when the blood radioactivity of 111In-BLM 5 minutes after the injection was counted as 100%, about 80% of the radioactivity was cleared from the blood in 48 hours. Over 50% of the radioactivity was excreted into the urine in 48 hours.<BR>3) Of 29 cases of female genital malignant tumors, 23 cases (79%) showed positive images. Therefore 111In-BLM was found to be one of the suitable radiopharmaceuticals for the diagnosis of female genital malignant tumors.<BR>4) 111In-BLM scintigraphy was of great use for deciding the extent of the invasion of carcinoma cervicis uteri into parametrium and for the search of metastasis.

Journal

  • RADIOISOTOPES

    RADIOISOTOPES 27 (9), 514-519, 1978

    Japan Radioisotope Association

Keywords

Details 詳細情報について

Report a problem

Back to top