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Synthetic Utility of tert-Butyl Azidoacetate on the Hemetsberger-Knittel Reaction. Synthetic Studies of Indoles and Related Compounds. Part 47.
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Description
The synthetic utility of tert-butyl azidoacetate (7) on the Hemetsberger-Knittel reaction is described. The following two findings are disclosed by using tert-butyl azidoacetate (7) : i) in the first step for the synthesis of ethyl indole-2-carboxylate 4, the aldol reaction of less reactive aldehydes 1a, b was improved greatly; ii) tert-butyl indole-2-carboxylate 10 becomes readily available from aldehydes.
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 47 (9), 1227-1231, 1999
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390282679137129344
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- NII Article ID
- 130003947930
- 110003617405
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- NII Book ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL BIB ID
- 4856787
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed