Preparation of Core Particles for Aqueous Film Coating Using Agitation Fluidized Bed.
Bibliographic Information
- Other Title
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- Preparation of Core Particles for Aqueo
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Abstract
Core particles used for aqueous film coating were prepared by agitation fluidized bed granulation, and effect of the damping speed on the granule properties of mass median diameter, geometric standard deviation, apparent density, yield friability and specific surface area were investigated. Film coating by an aqueous acylic copolymer (Eudragit NE-30D) was carried out using the core particles granulated under three levels of damping speeds, and the drug release properties of each coated product were identified. Relationship between properties of core particles and the release properties were clarified and the optimal granulation conditions to make optimal core particles for film coating were determined.
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 45 (12), 2039-2042, 1997
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390282679138550144
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- NII Article ID
- 130003773675
- 110003662837
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- NII Book ID
- AA00602100
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- COI
- 1:CAS:528:DyaK1cXltl2k
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- ISSN
- 13475223
- 00092363
- http://id.crossref.org/issn/00092363
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- NDL BIB ID
- 4371075
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- PubMed
- 9433775
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed
