Castaneiolide, abscisic acid and monorden, phytotoxic compounds isolated from fungi (Macrophoma castaneicola and Didymosporium radicicola) cause "black root rot disease" in chestnut trees.

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Macrophoma castaneicola and Didymosporium radicicola are pathogens causing chestnut black root rot disease. A new metabolite, castaneiolide, and abscisic acid were isolated from M. castaneicola and monorden was from D. radicicola. These metabolites were toxic to chestnut leaves.

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