Antifungal and insecticidal activities of daphnodorins A, B and C.

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Three flavans, daphnodorin A (1), daphnodorin B (2) and daphnodorin C (3), isolated from the root and the bark of Daphne odora THUNB., showed antifungal and insecticidal activities. Of these compounds, 1 and 3 showed rather strong antifungal activities against Pyricularia oryzae. The protective values (%) of 1 and 3 were 58 and 40 at the low concentration of 10 ppm, respectively. On the other hand, compound 2 exhibited weak insecticidal activity against Spodoptera litura, Callosobruchus chinensis and Tetranychus urticae. The insecticidal activities of 1 and 3 were weaker than that of 2.

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