Constituents of Hypericum laricifolium and Their Cyclooxygenase (COX) Enzyme Activities

DOI Web Site PubMed 24 References
  • El-Seedi Hesham Rushdey
    Division of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University
  • Ringbom Therese
    Division of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University
  • Torssell Kurt
    Division of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University
  • Bohlin Lars
    Division of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University

Search this article

Description

Investigation of the aerial parts of the medicinal plant Hypericum laricifolium led to the isolation of two new natural products, hentriacontanyl caffeate (1a), nonacosanyl caffeate (1b). In addition, stigmasterol, β-sitosterol, 3-epi-betulinic acid (2), caffeic acid (3), ferulic acid, docosanol, p-hydroxybenzoic acid, 3,4-dimethoxy benzoic acid, quercetin (4), quercetin-3-O-galactoside (5), quercetin-3-O-rutinoside (6), quercetin-3-O-rhamnoside (7), quercetin-3-O-glucuronide (8) and shikimic acid were also isolated. The structures were determined by 1D- and 2D-NMR, mass spectrometry, and chemical transformations. The anti-inflammatory effects of the isolated compounds were discussed briefly.

Journal

References(24)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top