Jaspolides A-F, Six New Isomalabricane-Type Terpenoids from the Sponge Jaspis sp.

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  • Tang Shengan
    State Key Laboratory of Natural and Biomimetic Drugs, Peking Univesity College of Traditional Chinese Medicine, Shenyang Pharmaceutical University
  • Pei Yuehu
    College of Traditional Chinese Medicine, Shenyang Pharmaceutical University
  • Fu Hongzheng
    State Key Laboratory of Natural and Biomimetic Drugs, Peking Univesity
  • Deng Zhiwei
    Analytical and Test Center, Beijing Normal University
  • Li Jun
    State Key Laboratory of Natural and Biomimetic Drugs, Peking Univesity
  • Proksch Peter
    Institute of Pharmaceutical Biology, Heinrich Heine University Duesseldorf
  • Lin Wenhan
    State Key Laboratory of Natural and Biomimetic Drugs, Peking Univesity

書誌事項

公開日
2006
DOI
  • 10.1248/cpb.54.4
公開者
公益社団法人 日本薬学会

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説明

A chemical investigation of Jaspis sp., the marine sponge collected from the South China Sea led to the isolation of six new isomalabaricane-type compounds, jaspolides A—F (1—6). The structures of those compounds were elucidated by extensive spectroscopic methods. The structure-types of 1 to 6 could be classified into triterpenes (1, 2), sesterterpene (6), diterpenes (3, 4), and nortriterpene (5). The biogenetic transformation of the isolated compounds was also speculated.

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