Catalytic Activity of Silica Gels Bound Manganese(III)-Porphyrin on Oxidative Reaction of Adrenaline

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  • Kitamura Youji
    Department of Pharmaceutical Sciences, Graduate School of Medicine and Dentistry and Pharmaceutical Sciences, Okayama University
  • Takatsuki Tsutomu
    Department of Pharmaceutical Chemistry, Graduate School of Natural Science and Technology, Okayama University
  • Kawamoto Mayu
    Department of Pharmaceutical Chemistry, Graduate School of Natural Science and Technology, Okayama University
  • Saito Madoka
    Department of Pharmaceutical Chemistry, Graduate School of Natural Science and Technology, Okayama University Faculty of Medicine, Kagawa University
  • Iwado Akimasa
    Department of Pharmaceutical Sciences, Graduate School of Medicine and Dentistry and Pharmaceutical Sciences, Okayama University
  • Tsukamoto Ikuko
    Faculty of Medicine, Kagawa University
  • Mifune Masaki
    Department of Pharmaceutical Sciences, Graduate School of Medicine and Dentistry and Pharmaceutical Sciences, Okayama University
  • Saito Yutaka
    Department of Pharmaceutical Sciences, Graduate School of Medicine and Dentistry and Pharmaceutical Sciences, Okayama University

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  • Catalytic Activity of Silica Gels Bound Manganese(3)-Porphyrin on Oxidative Reaction of Adrenaline

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Abstract

To develop a solid catalysis on oxidative reaction of adrenaline (Ad), supports bound metal-tetrakis(4-carboxyphenyl)porphine (M-TCPP) were investigated. Silica gels bound Mn-TCPP were proved to has a superior activity in the oxidation of Ad and be able to serve as a useful oxidase model for Ad.

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