Sequence Fourier Analysis of a Specific Protein-DNA (RNA) Interaction; an Intermolecular Frequency Symmetry
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- Numao Naganori
- BioFrontier Institute Inc.
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- Kamimoto Yoshihito
- Kanagawa Industrial Technology Center
Bibliographic Information
- Other Title
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- Communications to the editor: Sequence Fourier analysis of a specific protein-DNA (RNA) interaction: an intermolecular frequency symmetry
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Abstract
Here, we first report that a specific protein–DNA (RNA) interaction between p53 protein and divergent I kappa B kinase interacting protein (IKIP)-Apaf1 DNA promoter region, and between poliovirus 3CD protein and the 5′ terminal region of the RNA sequence can be successfully elucidated with a sequence Fourier analysis, alike various specific protein–protein interactions described previously. Based on these, the intermolecular frequency symmetry would be evolutionarily conserved in a specific interaction of the bioactive structure of various long-chain sequences. In addition, the symmetry is fairly sensitive to a substitution (or a point mutation) on the sequence.
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 57 (11), 1305-1307, 2009
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390282679146073856
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- NII Article ID
- 130000124830
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- NII Book ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL BIB ID
- 10412684
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed