Molecular Weight Determination of Hypromellose Acetate Succinate (HPMCAS) Using Size Chromatography with a Muiti-Angle Laser Light Scattering Detector
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- Fukasawa Miyuki
- Specialty Chemicals Research Center, Shin-Etsu Chemical Co., Ltd.
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- Obara Sakaé
- Specialty Chemicals Research Center, Shin-Etsu Chemical Co., Ltd.
書誌事項
- タイトル別名
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- Molecular Weight Determination of Hypromellose Acetate Succinate (HPMCAS) Using Size Exclusion Chromatography with a Multi-Angle Laser Light Scattering Detector
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説明
The molecular weight of hypromellose acetate succinate (HPMCAS), a polymer used for enteric coating, was determined by means of size exclusion chromatography with a multi-angle laser light scattering detector. The weight-average molecular weight (Mw) of several lots and grades ranged approximately from 17000 to 20000, and the number-average molecular weight (Mn) was around 13000. The inter-day precision of measurement, in terms of the coefficient of variation, was less than 5%.
収録刊行物
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- ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ
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ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ 52 (11), 1391-1393, 2004
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679146354432
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- NII論文ID
- 110003665460
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 7129744
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- PubMed
- 15516773
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
