Design and evaluation of cyclodextrin-based drug formulaiton
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- Uekama Kaneto
- Graduate School of Pharmaceutical Sciences, Kumamoto University
書誌事項
- タイトル別名
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- Design and Evaluation of Cyclodextrin-Based Drug Formulation
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説明
The pharmaceutically useful cyclodextrins (CyDs) are classified into hydrophilic, hydrophobic, and ionic derivatives. Because of the multi-functional characteristics and bioadaptability, these CyDs are capable of alleviating the undesirable properties of drug molecules through the formation of inclusion complexes or the form of CyD/drug conjugates. This review outlines the current application of CyDs in design and evaluation of CyD-based drug formulation, focusing on their ability to enhance the drug absorption across biological barriers, the ability to control the rate and time profiles of drug release, and the ability to deliver a drug to a targeted site.
収録刊行物
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- ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ
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ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ 52 (8), 900-915, 2004
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679146637696
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- NII論文ID
- 110003615686
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- NII書誌ID
- AA00602100
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- COI
- 1:CAS:528:DC%2BD2cXmvVKktbg%3D
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- ISSN
- 13475223
- 00092363
- http://id.crossref.org/issn/03851605
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- NDL書誌ID
- 7020432
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- PubMed
- 15304981
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可
