Synthesis and antimicrobial activity of some 5-substituted-3-phenyl-Nβ-(substituted-2-oxo-2H-pyrano〔2,3-b〕quinoline-3-carbonyl)-1H-indole-2-carboxyhydrazide
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- Suliphal Devara Mathada Basavarajaiah
- Department of Studies and Research in Chemistry, Gulbarga University
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- Bennikallu Hire Mathada Mruthyunjayaswamy
- Department of Studies and Research in Chemistry, Gulbarga University
書誌事項
- タイトル別名
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- Synthesis and Antimicrobial Activity of Some 5-Substituted-3-phenyl-N.BETA.-(Substituted-2-oxo-2H-pyrano[2,3-b]quinoline-3-carbonyl)-1H-indole-2-carboxyhydrazide
- Synthesis and antimicrobial activity of some 5 substituted 3 phenyl N v substituted 2 oxo 2H pyrano 2 3 b quinoline 3 carbonyl 1H indole 2 carboxyhydrazide
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説明
Ethyl 3-oxo-3-{2-[(5-substituted-3-phenyl-1H-indol-2-yl)carbonyl]hydrazinyl}propanoates 5a—b were synthesized according to the literature method. These on further reaction with substituted-2-hydroxy-3-formylquinolines 3a—e yielded 5-substituted-Nβ-(2-oxo-2H-pyrano[2,3-b]quinoline-3-carbonyl)-3-phenyl-1H-indole-2-carbohydrazides 6a—j. Structures of the all the newly synthesized compounds were confirmed by spectral data. All these compounds have been screened for their antibacterial activity against Staphylococcus aureus, Escherichia coli and Bacillus subtilus, antifungal activity against Aspergillus niger and Candida albicans and antituberculosis activity against Mycobacterium tuberculosis (H37Rv).
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 57 (6), 557-560, 2009
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679146921344
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- NII論文ID
- 130000124339
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 10234751
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
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- 使用不可