A New Ferulic Acid Ester and Other Constituents from Tamarix nilotica Leaves

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  • Abouzid Sameh Fekry
    Department of Pharmacognosy, Faculty of Pharmacy, Beni-Sueif University
  • Ali Sajjad Ahmed
    H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi
  • Choudhary Muhammad Iqbal
    H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi

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  • A new ferulic acid ester and other constituents from Tamarix nilotica

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Phytochemical investigation of the leaves of Tamarix nilotica (Tamaricaceae) has led to isolation of methyl ferulate 3-O-sulphate (1) for the first time from natural sources. In addition, coniferyl alcohol 4-O-sulphate (2), kaempferol 4′-methyl ether (3), tamarixetin (4) and quercetin 3-O-β-D-glucupyranuronide (5) were isolated from the n-butanol soluble fraction of the extract. The pentacyclic triterpenoid, 3α-(3″,4″-dihydroxy-trans-cinnamoyloxy)-D-friedoolean-14-en-28-oic acid (6) was isolated from the n-hexane soluble fraction of the extract. The structures of these compounds were determined on the basis of spectroscopic analyses including 2 dimensional NMR. Compounds 3, 4 and 6 exhibited 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity with IC50 values of 35.2, 37.0 and 21.2 μM, respectively.

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