Briaexcavatins M-P, Four New Briarane-Related Diterpenoids from Cultured Octocoral Briareum excavatum (Briareidae)

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  • Sung Ping-Jyun
    Taiwan Coral Research Center and Department of Planning and Research, National Museum of Marine Biology & Aquarium Institute of Marine Biotechnology, National Dong Hwa University Asia-Pacific Ocean Research Center, National Sun Yat-sen University
  • Lin Mei-Ru
    Taiwan Coral Research Center and Department of Planning and Research, National Museum of Marine Biology & Aquarium Department of Marine Biotechnology and Resources, National Sun Yat-sen University
  • Hwang Tsong-Long
    Graduate Institute of Natural Products, Chang Gung University
  • Fan Tung-Yung
    Taiwan Coral Research Center and Department of Biology, National Museum of Marine Biology & Aquarium Institute of Marine Biodiversity and Evolution, National Dong Hwa University
  • Su Wei-Chun
    Taiwan Coral Research Center and Department of Biology, National Museum of Marine Biology & Aquarium
  • Ho Chiu-Chin
    Taiwan Coral Research Center and Department of Biology, National Museum of Marine Biology & Aquarium
  • Fang Lee-Shing
    Institute of Marine Biodiversity and Evolution, National Dong Hwa University Department of Sport, Health, and Leisure, Cheng Shiu University
  • Wang Wei-Hsien
    Taiwan Coral Research Center and Department of Planning and Research, National Museum of Marine Biology & Aquarium Department of Marine Biotechnology and Resources, National Sun Yat-sen University

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Four new briarane-related diterpenoids, designated as briaexcavatins M—P (1—4), were isolated from the cultured octocoral Briareum excavatum. The structures, including the relative configurations of natural products 1—4 were established on the basis of extensive spectral data analysis and by comparison with the spectral data from other known metabolites featuring a briarane carbon skeleton.

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