Immunosuppressive Diterpenes from Veronicastrum sibiricum

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  • Gao Wenyuan
    The College of Pharmaceuticals and Biotechnology, Tianjin University
  • Zhang Rong
    The College of Pharmaceuticals and Biotechnology, Tianjin University
  • Jia Wei
    The School of Pharmacy, Shanghai Jiao Tong University
  • Zhang Jun
    The School of Pharmacy, Tianjin Medical University
  • Takaishi Yoshihisa
    Faculty of Pharmaceutical Sciences, University of Tokushima
  • Duan Hongquan
    The College of Pharmaceuticals and Biotechnology, Tianjin University

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Abstract

Two new diterpenes, named sibiriquinone A (1) and B (2), along with four known diterpenes have been isolated from the aerial part of Veronicastrum sibiricum. Their structures were elucidated by spectroscopy. The isolated compounds showed significant immunosuppressive activities.

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