Antioxidative Phenols and Phenolic Glycosides from Curculigo orchioides

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  • Wu Qiong
    Research Center of Natural Medicines, Fudan University School of Life Sciences, Fudan University
  • Fu Da-Xu
    Research Center of Natural Medicines, Fudan University School of Life Sciences, Fudan University
  • Hou Ai-Jun
    Research Center of Natural Medicines, Fudan University Department of Pharmacognosy, School of Phamacy, Fudan University
  • Lei Guang-Qing
    Research Center of Natural Medicines, Fudan University School of Life Sciences, Fudan University
  • Liu Zhi-Jun
    Medicinal Plant Laboratory, School of Renewable Natural Resources, Louisiana State University Agricultural Center
  • Chen Jia-Kuan
    Research Center of Natural Medicines, Fudan University School of Life Sciences, Fudan University
  • Zhou Tong-Shui
    Research Center of Natural Medicines, Fudan University School of Life Sciences, Fudan University

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Description

A new orcinol glucoside, orcinol-1-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (3), was isolated from the rhizomes of Curculigo orchioides GAERTN., together with seven known compounds: orcinol glucoside (1), orcinol-1-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (2), curculigoside (4), curculigoside B (5), curculigoside C (6), 2,6-dimethoxyl benzoic acid (7), and syringic acid (8). The structures of these compounds were elucidated using spectroscopic methods. The antioxidant activities of these isolated compounds were evaluated by colorimetric methods based on their scavenging effects on hydroxyl radicals and superoxide anion radicals, respectively. All the compounds showed potent antioxidative activities and the structure–activity relationship is discussed.

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