Two New Drimane Sesquiterpenoids from Compound Changweikang and Their Inhibitory Activity against Nitric Oxide Production
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- Liu Ming-sheng
- School of Pharmaceutical Sciences, Hainan Medical University Hainan Provincial Key Laboratory of R&D of Tropical Herbs
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- Liu Chang
- School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
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- Zhang Xiao-po
- School of Pharmaceutical Sciences, Hainan Medical University
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- Sheng Lin
- School of Pharmaceutical Sciences, Hainan Medical University Hainan Provincial Key Laboratory of R&D of Tropical Herbs
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- Zhang Jun-qing
- School of Pharmaceutical Sciences, Hainan Medical University Hainan Provincial Key Laboratory of R&D of Tropical Herbs
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- Kang Sheng-li
- School of Pharmaceutical Sciences, Hainan Medical University Hainan Provincial Key Laboratory of R&D of Tropical Herbs
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Abstract
Two new drimane sesquiterpenoids, changweikangic acid A (1) and B (2), were isolated from Compound Changweikang. Their structures were established on basis of extensive spectroscopic analyses including two dimensional (2D) NMR and X-ray crystallographic data. The two compounds were evaluated for their inhibitory activity against nitric oxide production in lipopolysaccharide-activated macrophage cell line, RAW 264.7 cells.
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 58 (9), 1224-1226, 2010
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390282679149678848
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- NII Article ID
- 130000324599
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- NII Book ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL BIB ID
- 10796476
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed