Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander

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  • Bai Liming
    College of Chemistry and Chemistry Engineering, Qiqihar University
  • Zhao Ming
    College of Chemistry and Chemistry Engineering, Qiqihar University
  • Toki Asami
    Graduate School of Science and Technology, Niigata University
  • Sakai Jun-ichi
    Department of Chemistry and Chemical Engineering, Faculty of Engineering, Niigata University
  • Yang Xiao-yang
    Atmospheric Chemistry & Aerosol Division, Chinese Research Academy of Environmental Science
  • Bai Yuhua
    Department of Medicinal Chemistry, Pharmaceutical Department, Harbin Medical University
  • Ando Mariko
    Technical Division, School of Engineering, Tohoku University
  • Hirose Katsutoshi
    KNC Laboratories Co., Ltd.
  • Ando Masayoshi
    College of Chemistry and Chemistry Engineering, Qiqihar University

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Two new cardenolide monoglycosides, cardenolides B-1 (1) and B-2 (2) were isolated from Nerium oleander, together with oleagenin (3) which is the first isolated compound from natural sources. The structure of compounds 1—3 were established on the basis of their spectroscopic data.

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