Selective Mono-reduction of Pyrrole-2,5 and 2,4-Dicarboxylates

DOI Web Site Web Site PubMed 参考文献22件 オープンアクセス
  • Yasui Eiko
    Department of Applied Chemistry, Kogakuin University Department of Chemistry and Life Science, Kogakuin University
  • Tsuda Jyunpei
    Department of Applied Chemistry, Kogakuin University
  • Ohnuki Satoshi
    Department of Applied Chemistry, Kogakuin University
  • Nagumo Shinji
    Department of Applied Chemistry, Kogakuin University Department of Chemistry and Life Science, Kogakuin University

この論文をさがす

抄録

<p>Pyrrole-2,5-dicarboxylates were rapidly and selectively reduced to the corresponding mono-alcohol using 3 eq of diisobutylaluminum hydride at 0°C. Pyrrole-2,4-dicarboxylate showed the same reactivity; however, the selectivity decreased with pyrrole-3,4-dicarboxylate. When the nitrogen atom of the pyrrole-2,5-dicarboxylate is protected with a benzyl group, selective mono-reduction does not occur. Considering that furan-2,5-dicarboxylates did not give the corresponding mono-alcohol under the same conditions, the unprotected nitrogen atom of pyrrole apparently plays an important role in this selective mono-reduction.</p>

収録刊行物

参考文献 (22)*注記

もっと見る

関連プロジェクト

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ