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Acylation of pyridoxine (I) with fatty acid chloride in pyridine and chloroform at room temperature gave pyridoxine diacylates (II), which were verified to be the 3, 4-diacylates. The diacylates prepared and the triacylates obtained as a by-product are listed in Table I. The long-chain fatty acid derivatives (II) are stable to heat and soluble in fat. Pyridoxine 3, 4-dipalmitate (II b) showed a complete pyridoxine activity in mice by oral or dietary administration.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 9 (3), 182-186, 1961
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679153250816
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- NII論文ID
- 110003618591
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- NII書誌ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 9245491
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可