Metabolic Fate of 1-Ethynylcyclohexyl Carbamate. II. Studies on the Glucuronide excreted in the Urine of Humans receiving 1-Ethynylcyclohexyl Carbamate.

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  • Metabolic fate of 1-ethynylcyclohexyl carbamate,pt.2

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Abstract

Marked increase of urinary glucuronic acid was observed in rabbits administered with ECC. A glucuronide of the metabolite of ECC was separated from urine of man who received ECC orally and it was identified as the glucuronide of OH-ECC by the reaction of β-glucuronidase and subsequent paper chromatography.

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