A Fast Atom Bombardment Study on the Interaction of Anticodonic Nucleotides and Their Cognate Amino Acid

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  • Fast Atom Bombardment Study on the In

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It can be shown by molecular model building and semi-empirical calculation that a complex of four nucleotides (C4N) composed of three anticodonic bases and a discriminator base can discriminate its cognate amino acid by the lock and key relationship. Possible evidence for the detection of such complexes (the C4N and the C4N-amino acid complexes) are presented by using fast atom bombardment-mass spectroscopy.

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