Effect of Fermented Soybeans Containing <I>Bacillus subtilis</I> MC1 on Defecation, Fecal Properties and Fecal Microflora of Healthy Female Volunteers

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  • 納豆菌<I>Bacillus subtilis</I> MC1芽胞を含む納豆の摂取が健常成人女性の排便および糞便内菌叢に及ぼす影響
  • 納豆菌Bacillus subtilis MC1 芽胞を含む納豆の摂取が健常成人女性の排便および糞便内菌叢に及ぼす影響
  • Bacillus subtilis MC1 ガホウ オ フクム ナットウ ノ セッシュ ガ ケンジョウ セイジン ジョセイ ノ ハイベン オヨビ フンベンナイ キンソウ ニ オヨボス エイキョウ

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To evaluate the effects of natto fermented by Bacillus subtilis MC1 on defecation, fecal properties and fecal microflora, a crossover study was conducted in 44 healthy volunteers (female, 34.9±8.8 years old; mean±SD). The subjects were divided into two groups and given 40g natto (B.subtilis MC1 spores 2×1010cfu) and boiled soybeans (40g/day) for 14 days each. No effect of natto was found on the frequency of defecation, the volume of feces or fecal characteristics. The number of Bacillus bacteria was significantly increased after the natto administration period in comparison with the boiled soybean administration period (p<0.05), indicating that live B.subtilis MC1 spores reached the large intestine. On the other hand, the number of other bacteria showed no change in the natto administration period in comparison with the boiled soybean administration period.

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